Gene: Nubpl

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Name
nucleotide binding protein-like
MGI ID
MGI:1924076
Synonyms
2410170E07Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Nubpltm1b(KOMP)Wtsi HOM   Early adult 0.00
prenatal lethality prior to heart atrial septation Nubpltm1b(KOMP)Wtsi HOM   E15.5 0.00
increased circulating triglyceride level Nubpltm1b(KOMP)Wtsi HET Early adult 6.53×10-05

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 Expression

Anatomy Images Mutant Expr
Adrenal gland N/A 0.0% (0 of 2)
Aorta N/A 0.0% (0 of 2)
Blood vessel N/A 0.0% (0 of 2)
Bone N/A 0.0% (0 of 2)
Brain N/A 100% (2 of 2)
Brainstem N/A 100% (2 of 2)
Brown adipose tissue N/A 0.0% (0 of 2)
Cartilage tissue N/A 0.0% (0 of 2)
Cerebellum N/A 0.0% (0 of 2)
Cerebral cortex N/A 0.0% (0 of 2)
Eye N/A 0.0% (0 of 2)
Gall bladder N/A 0.0% (0 of 2)
Heart N/A 0.0% (0 of 2)
Hippocampus N/A 0.0% (0 of 2)
Hypothalamus N/A 0.0% (0 of 2)
Kidney N/A 100% (2 of 2)
Large intestine N/A 0.0% (0 of 2)
Liver N/A 0.0% (0 of 2)
Lower urinary tract N/A 0.0% (0 of 2)
Lung N/A 0.0% (0 of 2)
Lymph node N/A 0.0% (0 of 2)
Mammary gland N/A 0.0% (0 of 2)
Esophagus N/A 0.0% (0 of 2)
Olfactory lobe N/A 0.0% (0 of 2)
Ovary N/A 0.0% (0 of 2)
Oviduct N/A 50% (1 of 2)
Pancreas N/A 0.0% (0 of 2)
Parathyroid gland N/A 100% (2 of 2)
Peripheral nervous system N/A 0.0% (0 of 2)
Peyer's patch N/A 0.0% (0 of 2)
Pituitary gland N/A 0.0% (0 of 2)
Prostate gland N/A 0.0% (0 of 2)
Skeletal muscle tissue N/A 0.0% (0 of 2)
Skin N/A 0.0% (0 of 2)
Small intestine N/A 0.0% (0 of 2)
Spinal cord N/A 100% (2 of 2)
Spleen N/A 0.0% (0 of 2)
Stomach N/A 0.0% (0 of 2)
Striatum N/A 0.0% (0 of 2)
Testis N/A 50% (1 of 2)
Thymus N/A 0.0% (0 of 2)
Thyroid gland N/A 0.0% (0 of 2)
Trachea N/A 0.0% (0 of 2)
Uterus N/A 0.0% (0 of 2)
White adipose tissue N/A 0.0% (0 of 2)

LacZ Wholemount Images (0 tissues)

There are no LacZ Wholemount images for Nubpl

LacZ Section Images (0 tissues)

There are no LacZ Section images for Nubpl

Other associated LacZ Section Images (6 tissues)

postnatal mouse thumbnail image
Postnatal Mouse (6)

Kidney

trunk thumbnail image
Trunk (4)

Kidney

nervous system thumbnail image
Nervous System (2)

Brainstem

reproductive system thumbnail image
Reproductive System (2)

Testis

endocrine system thumbnail image
Endocrine System (1)

Parathyroid Gland

urinary system thumbnail image
Urinary System (1)

Kidney

No Embryo expression data was found for this gene.

Background staining occurs in adult wild type mice at a measurable rate.

Anatomy WT Expr
Adrenal gland 0.51%
Aorta 0.17%
Blood vessel 0.0%
Bone 0.0%
Brain 0.51%
Brainstem 0.34%
Brown adipose tissue 0.0%
Cartilage tissue 0.0%
Cerebellum 0.51%
Cerebral cortex 0.34%
Eye 0.0%
Gall bladder 0.0%
Heart 0.17%
Hippocampus 0.51%
Hypothalamus 0.34%
Kidney 3.39%
Large intestine 1.69%
Liver 0.0%
Lower urinary tract 0.17%
Lung 0.17%
Lymph node 0.0%
Mammary gland 0.0%
Esophagus 0.0%
Olfactory lobe 0.34%
Ovary 0.17%
Oviduct 0.0%
Pancreas 0.85%
Parathyroid gland 0.0%
Peripheral nervous system 0.17%
Peyer's patch 0.0%
Pituitary gland 0.17%
Prostate gland 2.03%
Skeletal muscle tissue 0.0%
Skin 0.0%
Small intestine 1.53%
Spinal cord 0.34%
Spleen 0.34%
Stomach 2.2%
Striatum 0.51%
Testis 0.85%
Thymus 0.0%
Thyroid gland 2.71%
Trachea 0.34%
Uterus 0.0%
White adipose tissue 0.0%
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
Anti-nuclear antibody assay
6 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
DSS Histology
8 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Eye Morphology: Images Slit Lamp
1 Images
Ear epidermis immunophenotyping
12 Images
Legacy Phenotype Associated Images

View all 86 images

 Human diseases caused by Nubpl mutations

Monarch supplied infographic (800x240)

The table shows similarity analysis between the mouse phenotypes and human phenotypes when the orthologous human gene is known to cause disease. Strong similarities may indicate paths for research.

Disease Similarity of
phenotypes
Matching phenotypes Source
Isolated Complex I Deficiency
Increased serum pyruvate ORPHA:2609
Mitochondrial Complex I Deficiency, Nuclear Type 21
OMIM:618242

 IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Nubpl.

There are 1 publication which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation. Scientific data (September 2017) PMC5827107

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nubpltm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Nubpltm1c(KOMP)Wtsi Wild type floxed exon (post-Flp) Mice
Nubpltm82891(L1L2_Bact_P) Targeting vectors
Nubpltm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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