Number of results: 2059
abnormal regulatory T cell number
No IMPC genes are currently associated with this phenotype
Synonym:
abnormal Treg cell number,
abnormal suppressor T cell number
Definition: deviation from the average count of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity
small lung
5 genes associated with this phenotype
Synonym:
decreased lung size
Definition: reduced size of the lung compared to controls
abnormal compact bone thickness
No IMPC genes are currently associated with this phenotype
Synonym:
abnormal cortical bone thickness
Definition: reduced or increased width of the superficial layer of compact bone
abnormal inspiratory capacity
2 genes associated with this phenotype
Synonym:
Definition: anomaly in the maximal volume of air that can be inspired after the end of a normal expiration
abnormal retinal vasculature morphology
107 genes associated with this phenotype
Synonym:
abnormal retina vasculature morphology
Definition: any anomaly of the structure or arrangement of blood vessels supplying the retina
abnormal trabecular bone morphology
2 genes associated with this phenotype
Synonym:
abnormal substantia trabecularis morphology,
abnormal spongy substance morphology,
abnormal spongy spongiosa morphology,
abnormal cancellous bone morphology,
abnormal spongy bone morphology
Definition: any structural anomaly of bone that has a lattice-like or spongy structure; it is highly vascular and contains intercommunicating spaces filled with bone marrow
abnormal memory B cell number
No IMPC genes are currently associated with this phenotype
Synonym:
Definition: anomaly in the number of distinctly differentiated long-lived B cells that are readily activated upon reencounter of an antigenic determinant; memory B cells differentiate from antigen-activated B cells which have been selected for expression of higher affinity immunoglobulin
abnormal plasma cell number
1 gene associated with this phenotype
Synonym:
abnormal plasmacyte cell number
Definition: anomaly in the number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin
increased plasma cell number
1 gene associated with this phenotype
Synonym:
plasma cell hyperplasia
Definition: greater number of terminally differentiated, post-mitotic, short-lived cells of the B cell lineage devoted to producing large amounts of immunoglobulin
increased Langerhans cell number
No IMPC genes are currently associated with this phenotype
Synonym:
Definition: increase in the number of stellate dendritic cells of myeloid origin, that appear clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus