IMPC Release Notes

IMPC

  • Release: 10.1
  • Published: 26 June 2019

Statistical Package

  • PhenStat
  • Version: 2.20.0

Genome Assembly

  • Mus musculus
  • Version: GRCm38

Summary

  • Number of phenotyped genes: 5,861
  • Number of phenotyped mutant lines: 6,255
  • Number of phenotype calls: 70,692

Data access

Highlights

Data release 10.1

Release notes:

This represents a minor data release.

  • Includes additional Acoustic Startle and Pre-pulse Inhibition (PPI) derived parameters for % Pre-pulse inhibition - Global. The formula was updated to relax derivation requirements. Specifically the update allows derivations to be calculated using 3 % PPI parameters rather than requiring all 4.
  • Updates to automated methods of detecting anomolous or missing data resulted in some extraneous datapoints being removed.
  • The embryonic day associated to Viability E14.5-E15.5 Secondary Screen was updated from E14.5 to E15.5
  • The process for generating genotype to phenotype associations for categorical parameters has been changed. A phenotpye call is made in the case where the data analysis for each individual sex is not significant, but analysis using the combined data from both sexes is significant.
  • Fixed issue analyzing Combined retina parameter resulting in more phenotype calls.

Data Reports

Lines and Specimens

Phenotyping Center Mutant Lines Baseline Mice Mutant Mice
JAX 1,226 8,413 35,252
TCP 546 7,104 24,892
HMGU 311 3,173 5,770
KMPC 43 869 1,067
MARC 232 1,877 3,776
MRC Harwell 596 5,893 15,626
RBRC 96 2,023 1,859
ICS 223 2,325 3,554
WTSI 1,329 4,540 21,316
BCM 597 4,572 17,476
UC Davis 1,056 4,156 23,749

Experimental Data and Quality Checks

Data Type QC passed QC failed issues
categorical 14,917,864 3,835 * 16,974 *
unidimensional 11,116,529 43,508 * 293,835 *
time series 13,444,019 2,615 * 11 *
text 192,175 11,124 * 45,751 *
image record 469,960 0 0

* Excluded from statistical analysis.

Distribution of Phenotype Annotations

Status

Overall

By Center

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More charts and status information are available from iMits.

Phenotype Associations

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Trends

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Previous Releases

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